Tusk had 48 hours to respond to the notification of withdrawal.
The EU said that no trade deal can be agreed on before Brexit takes effect. The EU put emphasis on providing clarity to European citizens, businesses, stakeholders and global partners early in the negotiations.
"Only once we have achieved sufficient progress on the withdrawal can we discuss the framework for our future relationship".
The paper, which sets the scene for two years of tough Brexit talks, has now been sent to European capitals before a full negotiating mandate is cemented at a summit on April 29.
Speaking in parliament later on Wednesday, May told lawmakers it was "the moment for the country to come together".
Liberal Democrat leader Tim Farron said Theresa May had been "taken to Tusk", as the guidelines showed "the strength of the EU in these negotiations and the carelessness of the UK Government in isolating themselves from our European allies".
The challenges prior to moving onto the next step of talks are sizable, however.
The fate of three million European Union citizens living in Britain and one million British people within the bloc's 27 other nations is at the top of leaders' agenda. Since the issue of foreigners taking jobs from British workers fueled the Brexit referendum, a solution pleasing both Brussels and London will not be easy.
"If [the UK] wants to achieve a constructive agreement, they should discuss only with the 27 as the European Union", he said.
France and Germany have led opposition to the parallel talks that Ms May had demanded.
"There is no such thing as a penalty for leaving the EU", he told journalists in Valletta, Malta, referring to the €60 billion or more in liabilities, which the Union will ask the United Kingdom to pay before leaving.
The Prime Minister has warned that if the United Kingdom is forced to leave the European Union without an agreement future co-operation on tackling terrorism and crime would be "weakened", prompting accusations of "blackmail".
'We already miss you, ' Tusk said. He will then give a press conference later in the day from the country.
Tusk dismissed suggestions May had attempted to use security co-operation as a "bargaining chip" by linking it to trade in her March 29 letter notifying Brussels of the UK's intention to quit.
Government sources familiar with discussions with Mr Tusk's office say they expect the guidelines will be "quite short and terse", and will concentrate on broad principles and objectives rather than detailed outcomes.
Boris Johnson said: "I want to stress one thing, the UK's commitment to the defence and security of this region, of Europe, is unconditional and it is not some bargaining chip".
On Thursday, Mr Tusk issued a thinly veiled warning to the United Kingdom not to try and play divide-and-rule with the other 27 member states as talks begin.
The two teams have met seven times in the Premier League, with undefeated Spurs on a four-game winning streak (W5, D2). Tottenham would, at least temporarily, cut Chelsea's lead to four points with a win.
She said she is struggling to get enough to eat amid food shortages. "The only coup here is against President Nicolas Maduro". One person was killed after a third day of protests turned violent in Venezuela on Thursday.
The ability to limit music to Spotify's paid tier may no longer be as valuable as it would have been a year ago, however. However, the move would allow Spotify to save on the pricey underwriting fees associated with an IPO, said WSJ sources.
And McDonald's Corp. has stopped using chickens raised with antibiotics important to human medicine for its McNuggets. More information about these changes and additional ingredient work are available at kfc.com/responsibility .
It also has more stable, stronger 802.11ac Wi-Fi, the new Fire TV user interface and comes bundled with an Alexa Voice Remote. Vice President of Amazon Devices International, Jorrit Van der Meulen said: "This is a big day for Fire TV customers".
Closing arguments over two days capped a three-week trial and enabled jurors to begin deliberations in late afternoon. In an agreement with the Security and Exchange Commission, Mickelson agreed to repay the trading profits.
She said "The allegation is that somehow Obama administration officials utilized intelligence for political purposes". This official and two other intelligence officials said the NSA often receives dozens of such requests in a month.
At 65-14, the team is now 4.5 games clear of the San Antonio Spurs, who are going to play as the No. 2 seed in the playoffs. This gives Golden State a nice excuse to rest Curry, possibly for multiple games, going into the playoffs.
Johnson takes another shot at the Ultimate Fighting Championship ( UFC ) light heavyweight gold against Daniel Cormier. Thirty-eight-year-old Cormier came out that contest victorious, defeating Johnson via third round submission.
Young released "Rockin' in the Free World", a critique of the first George Bush administration, on the Freedom album in 1989. Besides the induction ceremony Friday night at Barclays Center, Lenny Kravitz will pay tribute to Prince.
The North has defied the ban, saying it infringes on its sovereign rights to self-defence and the pursuit of space exploration. President Donald Trump and Chinese President Xi Jinping. "That decision would be up to the president", he told reporters.
After almost every game, triple-double or not, Westbrook deals with reporters asking him whether he's chasing stats or not. Westbrook made just six-of-25 shots from the field, his worst shooting night of the season.
Share with Us - We'd love to hear eyewitness accounts, the history behind an article, and smart, constructive criticism. He added that the value of the Arctic's mineral riches was estimated to be US$30 trillion (S$41.8 trillion).
Experts say there is no way Romney will run for the seat without Hatch's blessing. 'I've had some conversations w mitt Romney . And as the first LDS presidential nominee, he unsurprisingly carried Utah with 73 percent of the vote.
The remains of the second person discovered about 20 miles away from Kansas City have not yet been identified, police said. Almost 10 years earlier, Yust had been seen with Kopetsky multiple times in the months leading up to her disappearance.
The launches are considered to be in violation with the corresponding resolution adopted by the United Nations. Mr Chang said Chinese leader Xi Jinping would have considered the strike as a "sign of disrespect to him".
But creatively, YouTube has done a stellar job of showcasing TV in a new way, for the mobile generation. The app was launched in a limited beta covering some 60,000 users in February, a Google spokesman said.
A Go Fund Me fundraising page has been set up to pay for the family's medical bills has already raised almost £25,000. Since the incident, Tysen has been on life support at a Children's Hospital at the University of MI in Ann Arbor .
Cardinals RF Stephen Piscotty (head contusion) appeared Thursday as part of a double-switch in the sixth inning and went 0-for-2. That pretty much leaves one explanation: Either the ball or his chest protector was really, really sticky. "Have never seen it".
Ora is said to have delivered her youngster smoothly following a four-hour labour bringing an end to her 15-month pregnancy. Once sign labor is close is when a giraffe's water breaks, which can be a trickle of liquid or a heavier flow of mucus.
However the star has been keeping a mysteriously low profile lately, which has led to speculation about her future plans. Gigi Hadid, one of Taylor Swift's many best girlfriends said previous year that the singer was busy making music.
At first it seemed Klopp might not fancy him but during the second half of last season it appeared he'd become the golden boy. What's more , only one Brazilian has played more games in Premier League history: Lucas Leiva, with 240.
The world's biggest social network will soon begin doing more to battle a continued problem online: revenge porn. These users will be immediately alerted that the picture they are trying to share violates Facebook's policies.
With Chelsea, Arsenal, Manchester City and Liverpool still to play, there seems no way back for the Teesside club. Last night may have brought the attacking football the Boro fans had craved for so long, but it was to no avail.